Unique 4-in-1 Formula for Arthritis and Joints             
"Let Nature Ease Your Pain™".

Product Information

In the short time this revolutionary product has been available to the public, thousands of ArthroSoft® 4-in-1 users have already found relief from arthritis and joint inflammation -- with very effective results!

Algonot researchers have created this unique natural formula, ArthroSoft®, which can help relieve many of the symptoms associated with arthritis. ArthroSoft® is not a cure, but it does reduce inflammation and promote the rebuilding of cartilage and helps relieve the swelling. ArthroSoft® also blocks the triggers that cause mast cells to release their secretions.

ArthroSoft® has the anti-inflammatory power of chondroitin & quercetin. We use glucosamine sulfate and chondroitin sulfate to help rebuild cartilage and surrounding tissues, as well as help reduce swelling. Quercetin, a natural flavanoid reduces inflammation. People who have taken ArthroSoft 4-in-1 have shown to suffer fewer symptoms of arthritis from the healing power of glucosamine sulfate and chondroitin sulfate.

Other products offer many of the same benefits of chondroitin and quercetin. Only ArthroSoft® uses unprocessed virgin kernel olive oil. This oil helps increase your body's absorption of the natural compounds and adds a powerful and important antioxidant property to ArthroSoft®.

Glucosamine
A key ingredient in the formation of joint cartilage, glucosamine sulfate is also present in the soft material between bones and joints and has mild anti-inflammatory abilities.

Chondroitin
Chondroitin is the main component of cartilage; it also forms the connective tissue that holds muscles, nerves, and blood vessels together. Chondroitin also inhibits the release of enzymes that trigger joint destruction.

Quercetin
Since quercetin is a natural ingredient (flavanoid) with potent anti-inflammatory capabilities, quercetin is added to Algonot Plus® to help relieve the swelling and protect from further damage associated with mast cell degranulation diseases. The quercetin we use comes from the saphora plant and not from fava beans.

Kernel Olive Oil
Olive seed oil is a potent anti-oxidant that can help reduce the risk of certain kinds of cancer. Olive seed oil plays an important role in Algonot Plus® products because it actually helps the body to absorb chondroitin and quercetin. We use only virgin olive seed oil from the island of Crete.

ArthroSoft® is not a cure and it may or may not offer immediate relief of pain and suffering. As Arthritis takes years to develop it takes time to reverse the damage done to the joints and surround tissues. It can take up to 90 days for ArthroSoft® to offer you relief from the symptoms of arthritis. People who have already started an Algonot Plus® regiment will not notice a significant increase in relief. ArthroSoft® does come in a smaller pill making it easier to take and less likely to cause stomach irritation. All Algonot® products should always be taken with a meal and only in suggested dosages. If you are allergic to eggs, fish or olive oil you should consult your doctor about ArthroSoft®.

All ingredients used in ArthroSoft® are natural and derived from foodstuffs. (For more information on exact ingredients please contact us at 1-800-ALGONOT or visit us on the web at www.algonot.com)

ArthroSoft® is the result of years of research into arthritis by Theoharis Theoharides, MD, PhD. Dr. Theoharides is a Professor of Pharmacology, Internal Medicine and Biochemistry in Boston. Algonot, LLC, is a corporation dedicated to combining scientific investigation with natural healing. An outstanding team of prominent physicians and scientists from Ivy League universities form its advisory board. With rigorous oversight our board helps ensure your trust and complete satisfaction with all Algonot® products.

Super Value Vitamins is an authorized retailer of Algonot Plus ArthroSoft® products.  Call toll-free at 1-866-966-1900 to order.

How It Works

Blocks
Algonot Plus starts working on inflammatory diseases on the cellular level, where these diseases begin. When allergens, stress, or other causes irritate mast cells, the cells react by secreting dangerous molecules that cause a chain reaction leading to activation of diseases such as osteoarthritis, rheumatoid arthritis, cystitis, and prostatitis. Algonot Plus blocks this process before it can start, by stopping the mast cells from becoming active, and also by blocking their ability to secrete dangerous substances.

Rebuilds and Protects
Algonot Plus also helps build new cartilage, and protects existing cells from further damage. Finally, Algonot Plus reduces the swelling associated with painful inflammatory diseases.

What makes Algonot products unique, when compared to others?

This is the only product that delivers enough of three active ingredients to the joints and other areas of body stress. One of these ingredients (glucosamine) helps the body synthesize new cartilage, the second (chondroitin sulfate) is readily incorporated into damaged cartilage and prevents it from further erosion, while the third ingredient (quercetin) reduces the inflammation that destroys the joint and causes stiffness and pain. In addition, the unique addition of olive seed oil, not only permits 3-5 times higher absorption of the three active ingredients, but adds its own antioxidants, such as vitamin E, that are helpful in reducing tissue damage and prolong its healthy function.

How safe are the dietary supplements from Algonot?

Algonot-Plus, unlike many other products, is made of entirely natural and pure ingredients. We have made sure that there is no potential danger. Glucosamine used in most of the available products sold in the USA is derived from cow trachea imported from Europe, in which case one runs the risk of possibly catching “mad cow disease.” The risk of mad cow disease is so serious in Europe that bovine gelatin has been banned from all cosmetic products

For this reason, the chondroitin sulfate in Algonot-Plus is obtained from shark cartilage imported from Latin America. For the same reason, the gelatin used for the shells of the capsules is obtained from pigs to avoid bovine material.

Are Algonot Products FDA approved? If not, do you see an FDA approval in the future?

Algonot-Plus is a food supplement and does not require FDA approval. This is why the description of this product focuses on prevention and strengthening of affected joints, rather than its being a “pain killer.” The label is reviewed by the FCC (Federal Trade Commission). It should, however, be pointed out that food supplements are not allowed to make any claims for treatment of any disease. This is why the label of Algonot-Plus states:

"Especially formulated, based on published scientific evidence, to work together delivering more of the bioactive ingredients to the joints and other sites of body stress."

Why do Algonot products contain olive seed oil?

Chondroitin Sulfate is one of the most important ingredients in any of the joint relief products currently on the market. But chondroitin is a composed of a very large molecule (with a molecular weight of 100,000 compared to glucose, for example, at less than 500). As a result, it is very hard to get the body to absorb chondroitin into tissues where it can do some good. Most chondroitin is flushed through the body and has no effect. Research has shown that combining this component with olive oil increases the amount absorbed by up to three times, more than 15% in many cases compared to less than 5% of chondroitin administered in regular pill form.

After oral administration of tritiated (3-H) chondroitin sulfate to the rat and dog, 70% of the radioactivity was absorbed BUT the high molecula weight fraction (THAT IS USEFUL) was about 10%. Additionally, if the degree of sulfation was high, the absorption WAS NEGLIGIBLE.

After intravenous administration of chondroitin sulfate (16,000 daltons) , more than 50% in exreted in the urine in the first 24 hours, while the absolute bioavailability (how much reaches the blood) after oral administration 1s 13.2%. Keep in mind that this size (16,000 daltons) has almost no protectivevalue in laboratory experiments.

The major excretion of both intramuscular and oral administration is in the urine. The size of chondroitin sulfate bigger than 4000 daltons (NOTE: the bigger the more effective, preferrably over 100,000 and highly sulfated) was only a few percent of the total administered. Six times more material had to be administered by mouth to reach the level administered intramuscularly .

They found NO absorption and considered the protection in the joints after oral administration an unfounded theory.

A medicinal preparation of low molecular weight (14,000 daltons) chondroitin sulfate (Condrosulf, Germany) was orally administered to male healthy volunteers in a single daily dose of 800 mg or in two doses of 400 mg each per day. The highest amount of 2.5 microg/ml was achieved in the blood 4-8 hr after admiistration and was down by 80% at 24 hours. Keep in mind that this size (14,000 daltons) has almost no protective value in laboratory experiments.
In the studies mentioned above, chondroitin sulfate was of small moelcular weight, low degree of sulfation and it was tritiated, a method that usually gives higher readings; yet., absorption ranged from 0-10% after oral administration.
When chondroitin sulfate of about double the size used in those studies (26,000 daltons) was used and was 14-C-labled, ONLY 0.4% of the oral dose administeredin rats was intact chondroitin sulfate in the blood, even though 4% was recovered intact in the urine (unpublished obervations). One is, therefore, forced to conclude that at best maybe 4% of roal chondroitin sulfate of molecular weight 26,000 daltons is absorbed from the intestine intact.

The companies selling chondroitin sulfate as food supplement for arthritis DO NOT provide information on the size or the degree of sultation of chondroitin sulfate. In other words, at best they may get 4% abosrption and at worst 0%. Yet. sales of chondroiin sulfate are about $0.5 billion per year in the USA. In fact, the MERCK INDEX (10th edition, 1983, p. 2190) lists chondroitin sulfate as having an evrage molecular weight of 50,000 daltons depending on the source and method of preparation. It is the gigher molecular weight and higher degree of sulfation that are biologically active in laboratory and clinical experiemtns, but it is these that are almost impossible to absopr orally in a powder form.
The innovation of Algonot-Plus is that chondroitin sulfate (together with glucosamine sulfate and quercetin) are mixed in unrefined olive seed oil, thus forming micelles that increase the absorption as the intestine is particularly suited for absorbing oils and lipids, while it exluded polarized molecules with ionic charges (sulftate).

How much Algonot Products should be taken and for how long?

One should start with one capsule in the morning and one in the evening with meals for one week. Two capsules should then be taken twice daily with meals for at least three months before any improvement is noticeable. Heavier individuals or those with long standing or severe symptoms would have to advance to two capsules three times per day after three months. Once the bottle is opened it should be preferably stored in the refrigerator or any other cool place.

The bottle should be shaken each time because the capsules may occasionally stick to each other when they are warm. Any “oily” smell does not mean anything other than the fact that the smell of the olive seed oil may be noticeable after a while, especially if the bottle is not kept cool.

Where can Algonot products be purchased?

Algonot products is only available in a select number of specialized retail vitamin stores.  Super Value Vitamins is an authorized retailer of Algonot Plus ArthroSoft® products.  Call toll-free at 1-866-966-1900 to order.